Publicaciones

Effects of culture densities on feed demand, behavioural tests and on the hepatic and cerebral oxidative status in tilapia (Oreochromis sp)

  • AUTORES:
    • María J Sánchez-Muros
    • Belén Sánchez
    • Fernando G Barroso
    • Sergio García-Mesa
    • Eva E Rufino-Palomares
    • José A Lupiáñez
    • Ana Sanz
  • REVISTA:
    • Applied Animal Behaviour Science
    • Volumen: 185
    • Páginas: 137-145
    • Año: 2016

The Oleanolic Acid Derivative, 3-O-Succinyl-28-O-benzyl Oleanolate, Induces Apoptosis in B16-F10 Melanoma Cells via the Mitochondrial Apoptotic Pathway

  • AUTORES:
    • Fernando J Reyes-Zurita
    • Marta Medina-O'donnell
    • Rosa M Ferrer-Martín
    • Eva E Rufino-Palomares
    • Samuel Martín-Fonseca
    • Francisco Rivas
    • Antonio Martínez
    • Andrés García-Granados
    • Amalia Pérez-Jiménez
    • Leticia García-Salguero
    • Juan Peragón
    • Khalida Mokhtari
    • Pedro P Medina
    • Andrés Parra
    • José A Lupiáñez
  • REVISTA:
    • RSC Advances
    • DOI: 10.1039/C6RA18879F
    • Año: 2016

Dietary arginine surplus does not improve intestinal nutrient absorption capacity, amino acid metabolism and oxidative status of gilthead sea bream (Sparus aurata) juveniles

Target molecules in 3T3-L1 adipocytes differentiation are regulated by maslinic acid, a natural triterpene from Olea europaea

  • AUTORES:
    • Amalia Pérez-Jiménez*
    • Eva E Rufino-Palomares*
    • Nieves Fernández-Gallego*
    • M. Carmen Ortuño-Costela
    • Fernando J. Reyes-Zurita
    • Juan Peragón
    • Leticia García-Salguero
    • Khalida Mokhtari
    • Pedro P Medina
    • José A Lupiáñez
  • REVISTA:

NADPH production, a growth marker, is stimulated by maslinic acid in gilthead sea bream by increased NADP-IDH and ME expression

  • AUTORES:
    • Eva E Rufino-Palomares*
    • Fernando J. Reyes-Zurita
    • Leticia García-Salguero
    • Juan Peragón
    • Manuel de la Higuera
    • José A Lupiáñez
  • REVISTA:
    • Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology,
    • Volumen 187
    • Páginas: 32-42
    • doi:10.1016/j.cbpc.2016.05.002
    • Año: 2016

Maslinic acid, a natural triterpene, induces a death receptor-mediated apoptotic mechanism in Caco-2 p53-deficient colon adenocarcinoma cells.

  • AUTORES:
    • Fernando J. Reyes-Zurita
    • Eva E Rufino-Palomares*
    • Leticia García-Salguero
    • Juan Peragón
    • Pedro P Medina
    • Andrés Parra
    • Marta Cascante
    • José A Lupiáñez
  • REVISTA:
    • PLoS ONE
    • Volumen 11 (1)
    • Páginas: 1301-1311
    • IF: 4.411 doi: 10.1371/journal.pone.0146178
    • Año: 2016

Dietary glutamine supplementation effects on amino acid metabolism, intestinal nutrient absorption capacity and antioxidant response of gilthead sea bream (Sparus aurata) juveniles

  • AUTORES:
    • F Coutinho
    • C Castro
    • E Rufino-Palomares
    • B Ordoñez-Grande
    • MA Gallardo
    • A Oliva-Teles
    • H Peres
  • REVISTA:
    • Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology
    • Volumen: 191
    • Páginas: 9-17 (A)
    • Año: 2016
    • IF: 2.1 doi:10.1016/j.cbpa.2015.09.012

A New HPLC-MS Method for Measuring Maslinic Acid and Oleanolic Acid in HT29 and HepG2 Human Cancer Cells.

  • AUTORES:
    • Juan Peragón
    • Eva Rufino-Palomares
    • Irene Muñoz-Espada
    • Fernando J. Reyes-Zurita
    • José A Lupiáñez
  • REVISTA:
    • International Journal of Molecular Sciences
    • Volumen 16 (9)
    • Páginas: 21.695-21.710
    • IF: 2,862 doi:10.3390/ijms160921681
    • Año: 2015

Maslinic acid, a triterpene from olive, affects the antioxidant and mitochondrial status of B16F10 melanoma cells grown under stressful conditions.

  • AUTORES:
    • Khalida Mokhtari
    • Eva Rufino-Palomares
    • Amalia Pérez-Jiménez
    • Fernando J. Reyes-Zurita
    • Celeny Figuera
    • Leticia García-Salguero
    • Pedro P. Medina
    • Juan Peragón
    • José A Lupiáñez
  • REVISTA:

Anti-cancer and anti-angiogenic properties of various natural pentacyclic triterpenoids and some of their chemical derivatives.

  • AUTORES:
    • Eva Rufino-Palomares
    • Amalia Pérez-Jiménez
    • Fernando J. Reyes-Zurita
    • Leticia García-Salguero
    • Khalida Mokhtari
    • Antonio Herrera-Marchán
    • Pedro P. Medina
    • Juan Peragón
    • José A Lupiáñez
  • REVISTA:

Expression inactivation of SMARCA4 by microRNAs in lung tumors.

  • AUTORES:
    • Coira, I
    • Rufino-Palomares, EE
    • Romero OA
    • Peinado P
    • Metheetrairut, C
    • Boyero Corral, L
    • Carretero, J
    • Farez-Vidal, E
    • Cuadros M
    • Fernando J. Reyes-Zurita
  • REVISTA:
    • Human Molecular Genetics
    • Volumen 24 (4)
    • Páginas: 1400-1409
    • doi: 10.1093/hmg/ddu554
    • Año: 2014

Premio al major paper del 2015 por la Real Academia de Medicina, Salamanca

Solid-phase library synthesis of bi-functional derivatives of oleanolic and maslinic acids and their cytotoxicity on three cancer cell lines.

  • AUTORES:
    • Parra, A
    • Martín-Fonseca S
    • Rivas, F
    • Reyes-Zurita FJ
    • Medina O'donell, M
    • Rufino-Palomares, EE
    • Martínez, A
    • García-Granados, A
    • José A Lupiáñez
    • Albericiio, F
  • REVISTA:
    • ACS combinatorial science
    • Volumen 16
    • Páginas: 128-447
    • doi 10.1021/co500051z
    • Año: 2014

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Antitumour activity on extrinsic apoptotic targets of the triterpenoid maslinic acid in p53-deficient Caco-2 adenocarcinoma cells.

  • AUTORES:
    • Fernando J. Reyes-Zurita
    • Eva E Rufino-Palomares
    • Pedro P Medina
    • Leticia García-Salguero
    • Juan Peragón
    • Pedro P Medina
    • Marta Cascante
    • José A Lupiáñez
  • REVISTA:
    • Biochimie
    • Volumen 95 (11)
    • Páginas: 2157-2167
    • doi: 10.1016/j.biochi.2013.08.017
    • Año: 2013

The role of maslinic acid in the pentose phosphate pathway during growth of gilthead sea bream (Sparus Aurata)

  • AUTORES:
    • Rufino-Palomares EE
    • Reyes-Zurita FJ
    • Garcia-Salguero L
    • Peragón J
    • De la Higuera M
    • Lupiáñez J.A
  • REVISTA:
    • Aquaculture Nutrition
    • Volumen: 19 (5) 09-720
    • doi: 10.1111/anu.12018
    • Año: 2013

Maslinic acid, a triterpenic anti-tumoural agent, interferes with cytoskeleton protein expression in HT29 human colon-cancer cells

  • AUTORES:
    • Rufino-Palomares EE
    • Reyes-Zurita FJ
    • Garcia-Salguero L
    • Mokhtari K
    • Medina PP
    • Lupiañez, JA
    • Peragón J
  • REVISTA:
    • Journal of Proteomics
    • Volumen: 3
    • Páginas: 5-25
    • doi: 10.1016/j.jprot.2013.02.031
    • Año: 2013

Mechanisms of SMARCA4 Inactivation in Lung

  • AUTORES:
    • Peinado P
    • Rufino-Palomares EE
    • Fernández-Coira I
    • Romero, O
    • Santamaría-Peiteado, R
    • Villacorta, L
    • Boyero, L
    • Reyes-Zurita FJ
    • Garcia-Salguero L
    • Lupiañez, JA
    • Sánchez-Céspedes, M
    • Medina PP
  • REVISTA:
    • Carcinogenesis Clinical & Translational Oncology
    • Volumen: 15
    • Año: 2013

Effect of maslinic acid food ration on the hepatic proteome of Sparus aurata

  • AUTORES:
    • Rufino-Palomares EE
    • Peragón J
    • Reyes-Zurita FJ
    • Mokhtari K
    • Garcia-Salguero L
    • Medina PP
    • Lupiañez, JA
  • REVISTA:
    • FEBS Journal
    • Volumen: 279
    • Páginas: 5-25
    • doi: 10.1016/j.jprot.2013.02.031
    • Año: 2013

17. Rufino-Palomares, E.E., Peragón, J, Reyes-Zurita, F.J., Mokhtari, K, García-Salguero, Medina, P.P., Lupiáñez, J.A. (2012) FEBS Journal, Volume 279, Issue Supplement s1, Pages 1–608, poster presentation: 52-576 DOI: 10.1111/j.1742-4658.2010.08705.x Descriptores de impacto: Science Edition–BIOCHEMISTRY & MOLECULAR BIOLOGY (JCR) Q2 Impact factor: 4.25 Number of citations: 0

18. Rufino-Palomares, E.E., Reyes-Zurita, F.J., García-Salguero, L., Peragón, J., De La Higuera, M., Lupiañez, J.A. (2012) Maslinic acid, a natural triterpene, and ration size increased growth and protein turnover of white muscle in gilthead sea bream (Sparus aurata) Aquaculture Nutrition 18 (5) 68–580 doi 10.1111/j.1365-2095.2011.00933. 19. Rufino-Palomares, E.E., Reyes-Zurita, F.J., García-Salguero, L., Peragón, J., De La Higuera, M., Lupiáñez, J.A. (2012) Maslinic acid and ration size enhanced hepatic protein-turnover rates of gilthead sea bream (Sparus aurata) Aquaculture Nutrition 18 (2) 138 - 151 doi: 10.1111/j.1365-2095.2011.00882.x

Maslinic acid, a natural triterpene, added to diet stimulates growth and protein turnover of white muscle in gilthead sea bream (Sparus aurata) cultured in farmed conditions

  • AUTORES:
    • Rufino-Palomares E
    • Reyes-Zurita F
    • Garcia-Salguero L
    • Peragón J
    • De la Higuera M
    • Lupiáñez J.A
  • REVISTA:
    • Aquaculture Nutrition
    • Año: 2011

Proteomics in the liver of gilthead sea bream (Sparus aurata) to elucidate the cellular response induced by the intake of maslinic acid

  • AUTORES:
    • Rufino-Palomares E
    • Reyes-Zurita F
    • Garcia-Salguero L
    • Peragón J
    • De la Higuera M
    • Lupiáñez J.A
  • REVISTA:
    • Proteomics
    • Volumen 11
    • Páginas 3312-3325
    • Año: 2011

The natural triterpene maslinic acid induces apoptosis in ht29 colon cancer cells by a jnkp53- dependent mechanism

  • AUTORES:
    • Reyes-Zurita F
    • Pachón-Peña G
    • Lizarraga D
    • Rufino-Palomares E
    • Cascante M
    • Lupiáñez J.A
  • REVISTA:
    • BMC Cancer
    • Páginas 11-154
    • Año: 2011

Maslinic acid and ration size enhanced hepatic protein-turnover rates of gilthead sea bream (Sparus aurata)

  • AUTORES:
    • Rufino-Palomares E
    • Reyes-Zurita F
    • García-Salguero L
    • Peragón J
    • De la Higuera M
    • Lupiáñez J.A
  • REVISTA:
    • Aquaculture Nutrition
    • DOI: 10.1111/j.1365-2095.0082.x
    • Año: 2011

Phenol metabolism in the leaves of the olive tree (Olea europaea L) cv. Picual, Verdial, Arbequina, and Frantoio during ripening

  • AUTORES:
    • Ortega-García F
    • Peragón J
  • REVISTA:
    • Journal of agricultural and food chemistry
    • Volumen: 58
    • Páginas: 12440-12448
    • Año: 2010

Dietary protein differentially regulates the kinetic behaviour of serine dehydratase and tyrosine aminotransferase of liver and white muscle of rainbow trout (Oncorhynchus mykiss)

  • AUTORES:
    • Peragón J
    • De la Higuera M
    • Lupiáñez J.A
  • REVISTA:
    • Comparative Biochemistry & Phisiology
    • Volumen: Part B: Biochemestry and molecular biology
    • Páginas: 213-219
    • Año: 2010

HPLC analysis of oleuropein, hydroxytyrosol, and tyrosol in stems and roots of Olea europaea L. cv. Picual during ripening

  • AUTORES:
    • Ortega-García F
    • Peragón J
  • REVISTA:
    • Journal of the science of food and agriculture
    • Volumen: 90
    • Páginas: 2295-2300
    • Año: 2010

Polyphenol Oxidase and Oleuropein in Olives and their Changes during Olive Ripening

  • AUTORES:
    • Ortega-García F
    • Peragón J
  • LIBRO:
    • In: Olives and olive oil in health and disease prevention
    • Edited by Victor R. Preedy and Ronald Ross Watson,
    • Oxford Academic Press. United Kingdom
    • Páginas: 233-238
    • ISBN: 978-0-12-374420-3
    • Año: 2010

Maslinic Acid: A Component of Olive Oil on Growth and Protein-turnover Rates

  • AUTORES:
    • Fernández-Navarro M
    • Peragón J
    • Esteban FJ
    • Amores U
    • De la Higuera M
    • Lupiáñez JA
  • LIBRO:
    • In: Olives and olive oil in health and disease prevention
    • Edited by Victor R. Preedy and Ronald Ross Watson,
    • Elsevier Limited Oxford Academic Press. United Kingdom
    • Páginas: 1415-1421
    • ISBN: 978-0-12-374420-3
    • Año: 2010

Antiproliferative effect of flavomannin-6,6'-Dimethylether from tricholoma equestre on caco-2 cells

  • AUTORES:
    • G. Pachón Peña
    • F.J. Reyes Zurita
    • G. Deffieux
    • A. Azqueta
    • A. López De Cerain
    • J. Centelles
    • E. Creppy
    • M. Cascante
  • REVISTA:
    • Toxicology
    • Volumen: 264
    • Páginas: 192-197
    • Año: 2009

Phenylalanine ammonia-lyase, polyphenol oxidase and phenols concentration in fruits of Olea europaea L. cv. Picual, Verdial, Arbequina, and Frantoio during ripening

  • AUTORES:
    • Ortega-García F
    • Peragón J
  • REVISTA:
    • Journal of the science of food and chemistry
    • Volumen: 57
    • Páginas: 10331-10340
    • Año: 2009

Maslinic acid, a natural triterpene from olea europaea l. , induces apoptosis in ht29 human colon-Cancer cells via the mitochondrial apoptotic pathway

  • AUTORES:
    • Reyes Zurita FJ
    • Rufino Palomares EE
    • Lupiañez Cara JA
    • Cascante M
  • REVISTA:
    • Cancer Letters
    • Volumen: 273
    • Páginas: 44-54
    • Año: 2009

Regulation of the kinetic behavior of serine dehydratase and tyrosine aminotransferase during the development of rainbow trout (Oncorhynchus mykiss)

  • AUTORES:
    • Peragón J
    • Aranda F
    • Garcia-Salguero L
    • De la Higuera M
    • Lupiañez Cara JA
  • REVISTA:
    • Aquaculture
    • Volumen: 293
    • Páginas: 119-124
    • Año: 2009

The response or phenylalanine ammonia-lyase, polyphenol oxidase and phenols to cold stress in the olive tree (Olea europaea L. cv. Picual)

  • AUTORES:
    • Ortega-García F
    • Peragón J
  • REVISTA:
    • Journal of the science of food and chemistry
    • Volumen: 89
    • Páginas: 1565-1573
    • Año: 2009

Phenylalanine ammonia-lyase and phenolic compounds in leaves and fruits of Olea europaea L. cv. Picual during ripening

  • AUTORES:
    • Ortega-García F
    • Blanco S
    • Peinado MA
    • Peragón J
  • REVISTA:
    • Journal of the science of food and chemistry
    • Volumen: 89
    • Páginas: 398-406
    • Año: 2009

Witch hazel (hamamelis virginiana) fractions and the importance of gallate moieties-Electron transfer capacities in their antitumoral properties

  • AUTORES:
    • Lizarraga D
    • Touriño S
    • Reyes Zurita FJ
    • De Kok J
    • Van Delft L
    • Mass J
    • Briede J
    • Centelles J
    • Torres JL
  • REVISTA:
    • Journal of agricultural and food chemistry
    • Volumen: 56
    • Páginas: 11675-11682
    • Año: 2008

Serine dehydratase and tyrosine aminotransferase activities increased by long-term starvation and recovery by re-feeding in rainbow trout (Oncorhynchus mykiss)

  • AUTORES:
    • Peragon J
    • Barroso JB
    • De la Higuera M
    • Lupiañez JA
  • REVISTA:
    • Journal of experimental zooloy, Part A: Ecological Genetics and physiology
    • Volumen: 309A
    • Páginas: 25-34
    • Año: 2008

Maslinic acid added to the diet increases growth and protein-turnover rates in the white muscle of rainbow trout (Oncorhynchus mykiss)

  • AUTORES:
    • Fernández-Navarro
    • Peragon J
    • Amores V
    • De la Higuera M
    • Lupiañez JA
  • REVISTA:
    • Comparative biochemistry & Physuiology Part C: Toxicololgy & Pharmacology
    • Volumen: 147
    • Páginas: 158-167
    • Año: 2008

Polyphenol oxidase and its relationship with oleuropein concentration in fruits and leaves of olive (Olea europaea) cv. "Picual" trees during fruit ripening.

  • AUTORES:
    • Ortega-García F
    • Blanco S
    • Peinado MA
    • Peragón J
  • REVISTA:
    • JTree Physioilogy
    • Volumen: 28 (1)
    • Páginas: 34-45
    • Año: 2008

(2á,3â)-2,3-Dihydroxyolean-12-En-28-Oic acid, a new natural triterpene from olea europea, induces caspase dependent apoptosis selectively in colon adenocarcinoma cells

  • AUTORES:
    • Reyes Zurita FJ
    • Centelles J
    • Lupiañez Cara JA
    • Cascante M
  • REVISTA:
    • FEBS Letters
    • Volumen: 580
    • Páginas: 6302-6310
    • Año: 2006

Maslinic acid as a feed additive to stimulate growth and hepatic protein-turnover rates in rainbow trout (Oncorhynchus mykiss)

  • AUTORES:
    • Fernández-Navarro
    • Peragon J
    • Esteban FJ
    • De la Higuera M
    • Lupiañez JA
  • REVISTA:
    • Comparative biochemistry & Physuiology Part C: Toxicololgy & Pharmacology
    • Volumen: 144 (2)
    • Páginas: 130-140
    • Año: 2006

Down-regulation in the expression of the rat-liver serine dehydratase during chronic metabolic acidosis

  • AUTORES:
    • López+-Flores I
    • Peragon J
    • Valderrama R
    • Esteban FJ
    • Luque F
    • Peinado MA
    • Aranda F
    • Lupiañez JA
    • Barroso JB
  • REVISTA:
    • American Journal of Physiology: Regulation, integrative and comparative physiology
    • Volumen: 291 (5)
    • Páginas: R1295-R1302
    • Año: 2006